As the name suggests, the threat management server is a server that acts as a router, firewall, antivirus program, VPN server, proxy server, and other threat management roles.
System Center 2016 Endpoint Protection is Microsoft's application for setting up a threat management server in an organization's network. To do it, you need to install and configure System Center 2016 Endpoint Protection. You can download System Center 2016 Endpoint Protection from the following URL:
https://www.microsoft.com/en-us/evalcenter/evaluate-system-center-2016.