More Housekeeping: Shutting Down and Restarting ArcMap
____ 36. Shut down ArcMap: Use File > Save (or its equivalent: Ctrl-S) to save your map file. Now click the “X” in the upper-right corner of the ArcMap window (or press Alt-F4) to close the ArcMap Program.
____ 37. Restart ArcMap. Unless someone has changed some settings, you will be given a choice of recent maps and near the top should be River_Map_3.mxd. Select it. You should see what you had before you terminated ArcMap.
____ 38. Stop and restart ArcMap using River_Map_3.mxd to invoke the program:
Again click the “X” in the upper-right corner of the ArcMap window. Now using Windows Explorer, navigate to
Pounce on it and ArcMap should open with the map you saved.
So you see that you can easily save your work, and easily restart ArcMap so that it will pick up where it left off.