Once you have user accounts and data loaded into your geodatabase, you then need to grant users access to the proper datasets for them to be able to utilize them. For example, as shown in the following screenshot, we have loaded a feature class under the data owner connection (owner login), but have not yet applied any privileges to it. As seen in the following screenshot, when we connect with the webreader account, that account does not have access to the feature class:
There are several ways to grant privileges on to tables through the user interface, geoprocessing, or Python.