November 2018
Beginner to intermediate
260 pages
5h 10m
Japanese
book
バイオビルダー ―合成生物学をはじめよう
by Natalie Kuldell, Rachel Bernstein, Karen Ingram, Kathryn M. Hart, 津田 和俊, 片野 晃輔, 西原 由実, 濱田 格雄
Content preview from バイオビルダー ―合成生物学をはじめよう
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123
BioBuilder
の「
iTune Device
」実験演習は、デザイ
ン／ビルド／テストのサイクルのうち、「テスト」の
フェーズに重きを置いています。あなたは、酵素を生
成する遺伝子回路を数種類扱うことになります。回路
は、その
DNA
配列にわずかな違いがあって、それによ
り細胞が生み出す酵素の量の変化が予期されます。回
路からの酵素のアウトプットを定量的に測定するため
には酵素アッセイ
［
31
］
を使います。また、すでに知られ
ている
DNA
配列のわずかな違いから起きる振る舞いに基づいて予想される結果と、実
際に得られた結果を比較します。
ほとんどの設計されたシステムでは、観察される振る舞いと予測される振る舞いの
間の大きな差異は許容できません。図
7-1
で指摘しているように、航空技術者は、飛行
機の機体に取り付けた際、予期しない飛び方をする新しい形状の尾翼をどう考えるで
しょうか？ そのような不確実性で設計と構築を行ったとしたら、膨大な費用がかか
り、潜在的に人命を危険にさらすことになります。もしも、単純なパーツ
（ナットやボ
ルト、あるいは抵抗や増幅器など）
の組み合わせが予期せぬ振る舞いを起こすとしたら、エ
ンジニアは設計を前に進めるのはほとんど不可能だと感じるでしょう。
より確立された工学分野では、さまざまな方法で機能的に組み立てることができる
モジュラーな構成要素のおかげで、個人のニーズにしたがい、その組み合わせを容易
31
̶
アッセイとは、分析や測定法のこと。酵素アッセイは、酵素活性を検出する方法を指す。 ...
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and much more.
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.