July 2024
Intermediate to advanced
280 pages
12h 52m
English
Content preview from The Essential Handbook of Polymer Terms and Attributes
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55 Enteric Coating
Enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment.
The first form of gastro-resistant coating was introduced by Unna in 1884 in the form of keratin-coated pills, although it was later discovered that they weren’t able to withstand gastric digestion. Salol was also used by Ceppi as one of the first forms of enteric coating. However, the first material that was extensively used as an enteric coating agent was shellac, starting with its introduction in 1930. Properly treated or hydrolyzed shellac showed different enteric-release properties.
Commonly used enteric-coating polymers are:
- Cellulose acetate phthalate ...
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